RESOURCES
Systematic review and meta-analysis of gallstone disease treatment outcomes in early cholecystectomy versus conservative management/delayed cholecystectomy.
Study/Year - Bagepally, et al., 2021
Patient Group - Symptomatic gallstone patients
Recommendation - Early cholecystectomy reduces biliary complications
Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial
Study/Year - C‑GALL trial, 2023
Patient Group - Uncomplicated symptomatic cases
Recommendation - Supports early cholecystectomy over conservative care
2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis
Study/Year - Pisano et al., 2020
Patient Group - Complicated gallstone disease
Recommendation - Guidelines: Index/early cholecystectomy recommended
Laparoscopic Cholecystectomy in Elderly Patients
Study/Year - Shrestha et al., 2025
Patient Group - Elderly with acute cholecystitis
Recommendation - Early surgery is safe and improves outcomes
Bibliography References
Kristensen SL, Rørth R, Jhund PS, et al. Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes Endocrinol. 2019;7(10):776-785. doi:10.1016/S2213-8587(19)30249-9
Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: cholelithiasis and cancer. Gut Liver. 2012;6(2):172-187. doi:10.5009/gnl.2012.6.2.172
Fanelli RD, Gersin KS. Laparoscopic endobiliary stenting: a simplified approach to the management of occult common bile duct stones. J Gastrointest Surg. 2001;5(1):74-80. doi:10.1016/s1091-255x(01)80016-0